Page 526 - Undergraduate Catalog 2024-25

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BMS 34130A - Cancer Biology I development of medical genetics; affecting cognitive function. This
Credit hours: 3 the spectrum of human autosomal involves neurotransmitters’ structure,
Prerequisite: BMS 34210A recessive diseases; localization function, and pharmacology, neuron-
and isolation of the Huntington glia interactions, intra-neuronal
The Cancer Biology course is a major disease gene; congenital diseases signaling, and the neurobiology of
course for Biomedical Sciences (BMS) caused by chromosomal imbalance; behavior and neurodegenerative
and Molecular & Medical Genetics diseases involving repeat expansions; disorders.
(MMG) programs designed to prepare developments and setbacks in the
students in their premedical studies use of gene and molecular therapies HMG 2201 - Introduction to
for future careers in these fields. This for treatment of hereditary diseases; Counselling Theory and Skills
course includes a comprehensive and pharmacogenomics (interaction Credit Hours: 3
description of all aspects of cancer of genetic background with drug Prerequisite: ENG200 + Completion
biology from the causes, and response). The course also covers of 45 Credit Hours
mechanistic view of dysregulation of analysis of quantitative traits:
cellular processes, to the diagnosis, complex human diseases such as Student are provided with
and treatment of cancer patients. type 2 diabetes and approaches to foundational philosophy and practice
The course summarizes the latest mapping genetic variants responsible information concerning counselling/
knowledge to date about cancer and for complex traits; heritability; and support work and professional ethics.
how the field is evolving. genome wide association mapping. They are introduced to the code of
Finally, the course explores transgenic ethics developed for health providers,
HMG 44130A - Inherited Cancer animals and gene therapy, stem cell with discussion on how to use this
Genetics biology and human evolutionary code as a guide to providing client
Credit Hours: 3 genetics. services. Applied exercises will help
Prerequisites: BMS 34130A + HMG HMG 442 - Inherited trainees practice identifying potential
442 ethical issues. Using theoretical
Immunodeficiencies principles and skills, making ethical
Although cancer is largely a Credit Hours: 3 reflections around guidance,
somatic genetic disease, several Prerequisite: BMS 34210A and searching evidence-based
predisposition mutations in key proto- information concerning medical
oncogenes and in particular tumour The course is designed to provide testing and counselling guidance are
suppressor genes are inherited. Thus, information on the genetic cause and covered. This will include identifying
the importance of predisposition cellular changes that occur in Primary possible psychological reactions in
will be covered in depth. The course immunodeficiencies. These can arise connection with health guidance.
will also explore cancer, genetics during development and others are
and epigenetics; stem cell theories inherited with a tendency towards HMG 2301 - Medical Genetic
of cancer and the importance of “genetic anticipations”. This course Counselling
the intestinal stem cells to cancer will explore the molecular genetic Credit Hours: 3
development and treatment; cancer basis of the various phenotypes and Prerequisite: HMG 2201
treatment including classical anti- a molecular genetic approach to their
cancer drugs such as antimetabolites, diagnosis and management. This course will be simulation
alkylating agents and antimitotic focused, with students demonstrating
agents and newer ‘magic bullet’ HMG 44110A - Inherited knowledge of different heredity
treatments; cellular and humoral Neurological Disorders patterns and family history
immune responses to tumors; and Credit Hours: 3 importance for heredity risks.
tumor immunotherapy. Prerequisite: BMS 34110A Students will be proficient in:
HMG 35110B - Principles of This course will provide the students making risk assessments based on
different inheritance patterns, taking
Medical Genetics with an in-depth understanding of the information about the family history
Credit Hours: 3 molecular mechanisms underlying and being able to draw a pedigree.
Co-requisite: BMS 34110B inherited neurological disorders, The limitations and ethical, legal, and
their diverse clinical presentations, social aspects of genetic testing and
The course introduces the genetics diagnostic methodologies, and results of these tests will be explored.
of human disease, from simple available treatment options.
Mendelian traits to complex The course will also cover the
multigenic diseases and gene/drug biochemistry of genetic deficiency
interactions. Topics include the disorders and metabolic diseases

Abu Dhabi University | Undergraduate Catalog 2024 - 2025